How LDN Helps Calm Histamine Reactions and Mast Cell Flare-Ups

Still dealing with unpredictable allergic symptoms—even without exposure to common triggers?

You might be dealing with Mast Cell Activation Syndrome (MCAS) or histamine intolerance. And here’s something you might not have heard from your allergist: Low-Dose Naltrexone (LDN) could be part of your solution.

What’s Going On With Mast Cells?

Mast cells are immune cells that release histamine—a chemical involved in allergic reactions, inflammation, and immune response. In MCAS or histamine intolerance, these cells are hyperactive, leading to chronic symptoms like:

• Hives and skin flushing

• Brain fog or fatigue

• Digestive issues

• Headaches or dizziness

• Temperature intolerance

This immune overreaction isn’t just frustrating—it’s exhausting.

How LDN Might Help

LDN is being explored for its ability to modulate the immune system, calming inflammation and reducing mast cell degranulation. Here’s why it’s gaining attention:

• Reduces histamine release from mast cells

• Stabilizes the immune system without immunosuppression

• A Milder Alternative compared to antihistamines or steroids

• May improve brain fog and mood symptoms triggered by histamine dysregulation

While research is still emerging, many patients report relief—especially when LDN is part of a broader, personalized treatment plan.

Your Next Step: Try LDN with Confidence

At Preston’s Pharmacy, we specialize in compounded LDN, offering customized dosing to match your needs. Whether you’re newly diagnosed or have tried everything else, we’re here to support you. Please call us on (571) 341-8787 or Email at info@prestonscompounding.com